To learn more about a specific study, click on the study name from the menu bar on the left or the study name below!
| Study | Aim and Eligibility |
| Pre-Prom | Aim: Compare the safety and effectiveness of subpectoral vs. prepectoral breast reconstruction Eligible: – Are a woman, aged 18 or over – Undergoing total mastectomy (surgery to remove the breast), for breast cancer or risk reduction, with immediate breast reconstruction using a tissue expander or implant (alloplastic breast reconstruction) – Are fluent in English |
| Flap-Prom | Aim: Understand the restoration of sensation using neurotization and non-neurotization in autologous breast reconstruction Eligible: – Are female, aged 19 or over – Are undergoing total mastectomy (surgery to remove the breast), for breast cancer or risk reduction, with immediate breast reconstruction using your own tissue (autologous breast reconstruction) with or without axillary surgery |
| Prediction Program | Aim: To assess how accurately machine learning models can predict individual complication risk after immediate breast reconstruction. Eligible: – Aged 19 or over – Are undergoing total mastectomy (surgery to remove the breast), for breast cancer or risk reduction, with immediate breast reconstruction (alloplastic or autologous) |
| Lymphedema QoL | Aim: Examine the Quality of Life in the lymphedema population before and after surgical intervention Eligible: – 18 years or older – Have lymphedema – Eligible for surgical intervention |
| Lymph Trial | Aim: Test whether lymphatic surgery provides better quality of life (QoL) compared to complex physical decongestion therapy (CDT) for patients with breast cancer-related lymphedema (BCRL). Eligible: – Patients ≥ 18 years of age with prior treatment of breast cancer. – At least one of the following prior breast cancer treatments: Sentinel lymph node biopsy (SLNB), axillary lymph node dissection (ALND), radiotherapy (RT) of chest wall or axilla or breast cancer surgery. – Clinical diagnosis of chronic BCRL as defined by the international society of lymphology (ISL; inter-limb difference of >10% in volume or excess volume between the affected and non-affected arm present for more than 3 months). – Minimum of 3 months CDT. – Ability to complete the QoL questionnaires. |
| Immediate Lymphatic Reconstruction (ILR) | Aim: To determine the effectiveness of ILR in preventing the development of lymphedema. We will compare two cohorts: one undergoing axillary lymph node dissection (ALND) alone, and another undergoing ALND with ILR. ALND is a surgery to remove lymph nodes from the underarms to check or treat breast cancer. ILR may be performed during ALND to reconnect lymphatic vessels and reduce the risk of lymphedema. Eligible: – Aged 19 or over – Are undergoing ALND with or without ILR surgery |